Candesartan CAS:139481-59-7 Moetsi oa Moetsi Setšoantšo se Hlahelitsoeng

Candesartan CAS: 139481-59-7 Mofani oa Moetsi

Candesartan ke mohanyetsi oa angiotensin II receptor I (AT1), IC50s=1.12 le 2.86 nM bakeng sa bovine adrenal cortex le rabbit aorta ka ho latellana.Ka khetho e thibela ho honyela ho bakoang ke angiotensin II ea li-aorta tsa mmutla tse se nang phello ka ho koenya ha li-nodpiine , KCl, serotonin, PGF2αkapa endothelin.

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Candesartan ke mohanyetsi ea khethiloeng oa AT1 (angiotensin II receptor 1).Ho hanyetsa ha li-angiotensin receptors ho thibela vasoconstriction le tlhahiso ea aldosterone, e lebisang ho fokotseha ha metsi le sodium ho plasma ea mali.E bonts'a litlamorao tsa antihypertensive mefuteng ea liphoofolo.E sebelisoa ho phekola ho hloleha ha pelo, joalo ka antihypertensive.Candesartan ha e ame ho sebetsa ha lisele kapa ho ata empa e eketsa ponahalo ea VEGF le interleukin-8 ka mokhoa o tloaelehileng oa lisele tsa KU-19-19.Candesartan (0.1 nM) e ka fokotsa karabelo e kholo ea contractile ho angiostensin II ka hoo e ka bang 50%.

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Sebopeho	Setšoantšo sa C24H20N6O3
Tlhahlobo	99%
Ponahalo	Phofo e tšoeu
Nomoro ea CAS.	139481-59-7
Ho paka	1KG 25KG
Shelf Life	lilemo tse 2
Polokelo	Boloka sebakeng se phodileng le se omileng
Setifikeiti	ISO.