2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate CAS:86520-63-0

2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate ke motsoako oa lik'hemik'hale o sebelisoang haholo lik'hemik'haleng tsa lik'habohaedreite le liketsong tsa glycosylation. Ke motsoako oa α-D-galactopyranose, mofuta oa tsoekere, moo lihlopha tsa hydroxyl tse maemong a 2, 3, 4, le 6 a lesale la galactopyranose li acetylated. Ho phaella moo, khabone ea anomeric (C1) ea tsoekere e sirelelitsoe ka sehlopha sa trichloroacetimidate, e leng se etsang hore e be electrophile e matla nakong ea liketso tsa glycosylation.

Hangata motsoako ona o sebediswa e le moemedi wa glycosylating ho kenya di-moieties tsa galactose ka hara dimolek'hule tse fapaneng, tse kang diprotheine, di-peptide, kapa dimolek'hule tse nyane tsa tlhaho. Sena se ka fihlellwa ka ho fetola motsoako ona ka nucleophile (mohlala, dihlopha tsa hydroxyl molek'huleng e rerilweng) tlasa maemo a loketseng. Sehlopha sa trichloroacetimidate se thusa ho hokela di-moiety tsa galactose ho molek'hule e rerilweng, e leng se fellang ka ho thehwa ha tlamo ya glycosidic.

Motsoako ona o sebediswa haholo ho kopanyeng di-glycoconjugate, di-glycopeptide le di-glycolipide. O fana ka mokgwa o feto-fetohang le o sebetsang wa ho fetola dimolek'hule tse nang le masala a galactose, e leng se ka bang bohlokwa mafapheng a fapaneng, ho kenyeletswa le dithuto tsa baeloji, ditsamaiso tsa ho fana ka meriana, kapa ntshetsopele ya diente.

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Glycosylation: Motsoako ona o arabela le limolek'hule tse fapaneng tsa receptor tse nang le lihlopha tsa hydroxyl, tse kang alcohols kapa amines, ho theha libonto tsa glycosidic. Sena se lumella ho kenngoa ha galactose ho molek'hule ea receptor, e leng se fellang ka ho kopanngoa ha li-glycoconjugates, li-glycopeptides, kapa li-glycolipids.

Lithuto tsa biochemical le baeloji: Motsoako ona o thusa bafuputsi ho ithuta mesebetsi ea baeloji le likamano tsa limolek'hule tse nang le galactose. Ka ho hokela galactose ka khetho ho liprotheine, li-peptide, kapa limolek'hule tse ling tsa biomolecule, bafuputsi ba ka batlisisa mesebetsi ea bona lits'ebetsong tsa sele, likamano tsa li-receptor-ligand le mekhoa ea mafu.

Mekhoa ea ho fana ka meriana: Motsoako ona o ka sebelisoa ho fetola limolek'hule tsa meriana tse nang le masala a galactose, ho nolofalletsa ho fana ka meriana e reretsoeng lisele kapa lisele tse itseng. Galactose e ka sebetsa e le ligand e shebaneng le eona, e lemoha li-receptor tse itseng tse hlahisoang holim'a lisele, haholo-holo li-hepatocyte. Ka ho hokela galactose lithethefatsing, bafuputsi ba ka ntlafatsa khetho ea bona le katleho ea bona kalafong e shebaneng le eona.

Ntlafatso ea liente: Limolek'hule tse nang le Galactose li bapala karolo ea bohlokoa likarabelong tsa 'mele oa ho itšireletsa mafung, kaha li tsejoa ke li-lectin tse teng liseleng tsa 'mele oa ho itšireletsa mafung. Ka ho kopanya li-antigen le likarolo tsa galactose ba sebelisa motsoako ona, bafuputsi ba ka ntlafatsa likarabelo tsa 'mele oa ho itšireletsa mafung le ho hlahisa liente tse sebetsang hantle haholoanyane.

Ho kopanngoa ha lik'hemik'hale: Motsoako ona o ka sebelisoa ho kopanngoa ha lik'hemik'hale tse fapaneng moo ho hlokahalang liphetoho tsa galactose. Sena se kenyelletsa ho lokisoa ha meaho e rarahaneng ea lik'habohaedreite, li-oligosaccharides, kapa li-glycomimetics, tse ka sebelisoang hape k'hemistri ea meriana kapa e le lisebelisoa tsa lipatlisiso.

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Tlhahisoleseling e 'Ngoe:

Sebopeho	C16H20Cl3NO10
Teko	99%
Ponahalo	Phofo e tšoeu
Nomoro ea CAS	86520-63-0
Ho paka	E nyane le e ngata
Bophelo ba Shelofo	lilemo tse 2
Polokelo	Boloka sebakeng se pholileng le se omileng
Setifikeiti	ISO.